For one of the shows I'm working on, we are running the band through an 01V, and then into the main board (a Mackie). During sound check, we used the Left main out from the 01V through the snake to a channel on the Mackie, and everything worked. Just as we started the run though, the band mix some weird noise that none of us had heard before. We tried a lot of things, until we switch to the Right main out on the 01V, and the issue went away. What I don't know, is what caused the issue to form, halfway through the day. Phantom power was on for some choir Mics. Is it possible that phantom power killed one of the outputs, and that it may do the same thing later?