Using Grog12's clock analogy, and presuming 12 to be upstage, I'd use 3-point from 12, 4, and 8; or better, 4-point from 1.5, 4.5, 7.5, and 10.5. Generally paler tints for frontlights: R05, 60, 03, and 53, (LtPnk, NcBlu, LtAmb, and PaleLav); are a good combination so no one side of the audience gets "cheated." DNLT is your friend to add deeper colors and interest. Depending on the size of the
stage, the FRLT alone can consume 24, 36, or 60 fixtures/channels.
Another analogy: when doing rock shows in the round, one method is to L,R,L,R,L,R,L,R the PA 360° around the
stage. Some audience sections experience the stereo
image "reversed," but it doesn't matter--it's still a stereo
image.
What is the show? We may be able to give more advice. If it's the C. Durang, I'd probably suggest everything
No Color and let the actors and words carry the message.